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GlucoseFIT

TM

There are several facets of blood sugar health: one is gluconeogenesis or how the liver produces glucose from various sugar precursors. Another is the conversion of starch (such as ingested grain) into glucose. GlucoseFIT™ made with plant extracts that work together to promote healthy glucose metabolism.

These botanical extract with scientific research works to support balanced sugar production in the liver, encourage healthy insulin sensitivity, inhibit sugar-digesting enzymes and promote healthy glucose elimination*.

Mulberry leaf extract

Mulberry leaf extract targets the alpha-glucosidase enzyme, which turns ingested starch into glucose.1,2 It also supports transporter compound GLUT4, which moves glucose out of the bloodstream and into muscle and liver cells.3 Mulberry promotes insulin sensitivity as well.4,5

  1. Molecules. 2019;24(9)
  2. S. National Library of Medicine. alpha-Glucosidases. Accessed 6/7/19. https://meshb.nlm.nih.gov/record/ui?name=alpha-Glucosidases
  3. Am J Chin Med. 2012;40(1):163-75.
  4. Medicine (Baltimore). 2018;97(34): e11996.
  5. PLoS One. 2017;12(2): e0172239.

SugaHeal

 The general condition for type 2 diabetic mellitus is:

  • Decrease in Glucose uptake/transport from the blood to Skeletal muscles and peripheral tissues.
  • This can be due to the condition of Insulin Resistance caused by Inflammatory cytokines and proteins.
  • Inflammation is the result of chronic obesity or permeability in the gut or other pathological stress conditions.

SugaHeal is standardized to 4-hydoxy isoleucine(4-HI) and Trigonelline from fenugreek seeds. Extract contains a synergistic blend of 20% 4HI and 20% Trigonelline to give a wholesome effect of both the molecules to support the healthy blood glucose level and reduce the variability in HbA1c readings in type 2 Diabetes mellitus.

The 4 Hydroxy isoleucine has a well-researched science which shows the insulinotropic properties and its potential as an anti-diabetic pharmacological compound and improves various conditions prevailing in Type 2 Diabetes mellitus through the following mechanism of action:

  • 4-Hydroxy Isoleucine(4-HI), a derivative of Isoleucine shows the Hypoglycaemic effect by uplifting the muscle uptake in skeletal muscles and peripheral tissues. The increased uptake of glucose through 4HI induced increase in GLUT4 translocation improves the blood glucose level and reduces the Hyperglycaemic conditions.
  • Liver synthesizes the glucose during fed state and stores in the form of glycogen. Hepatic insulin resistance prevents the conversion of stored glycogen into glucose when required mostly during fasting period which leads to the hypoglycaemic condition. 4-Hydroxy Isoleucine(4-HI), improves the hepatic insulin resistance by restoring Glycogen synthesis.
  • 4-Hydroxy Isoleucine(4-HI), improves the insulin resistance caused by inflammatory cytokines such as TNF-α induced by chronic obesity, High % of Free fatty acids.
  • Trigonelline improves the mitochondrial dysfunctions caused by oxidative stress via its potent antioxidant mechanism.
*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
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